DEPRESION EN  PACIENTES  CON  CANCER DE  SENO. RECOMENDACION PARA  TRATAR ANTES  DURANTE  Y  DESPUES  DE LOS PROCEDIMIENTOS  ONCOLOGICOS

En  este  interesante  estudio, se  revisa la situación  emocional del  paciente  oncológico. Ademas  de  la necesidad de  tratar esta  situación,muchas  veces  subclinica, generando por  supuesto  un mejor  pronostico  y bienestar  en  este  tipo de  experiencias.
Adicionalmente, mi sugerencia en la  coparticipación de  familiares  y  cercanos, que  muchas  veces  empeoran la  situación del  entorno.


Gen Hosp Psychiatr  |  Posted 6 days ago

Psychological and neuroendocrinological characteristics associated with depressive symptoms in breast cancer patients at the initial cancer diagnosisSeok JH, Kim LS, Hong N, Hong HJ, Kim SJ, Kang HJ, Jon DI; General Hospital Psychiatry 32 (5), 503-8 (2010 Sep-Oct)

OBJECTIVE: Breast cancer patients can have biopsychosocial changes induced by distress related to the cancer diagnosis. This study investigated psychological characteristics and hypothalamic-pituitary-adrenal (HPA) axis function associated with depressive symptoms in breast cancer patients at the initial diagnosis. METHOD: Seventy-eight breast cancer patients were enrolled, and 61 patients were included in the final analysis. Patients were evaluated concerning psychological adjustment to cancer diagnosis, self-concept and depressive symptoms and given a dexamethasone suppression test before the main surgical treatment. RESULTS: Self-concept scale scores and fighting spirit factor scores of the Korean version of the Mental Adjustment to Cancer (KMAC) scale showed inverse correlations. Anxious preoccupation (AP) factor scores of the KMAC scale positively correlated with depressive symptom scores. Depressive symptom scores were significantly correlated with postdexamethasone serum cortisol levels. In multiple regression analysis, postdexamethasone serum cortisol and the KMAC-AP factor score had significant partial effects in the final model. CONCLUSION: Hypothalamic-pituitary-adrenal axis dysfunction and anxious coping to cancer diagnosis may be associated with depressive symptoms in breast cancer patients before treatment. Based on this analysis, we recommend psychotherapeutic interventions to increase adaptive mental coping strategy and to ameliorate psychological distress. Screening for HPA axis dysfunction and provision of depression treatment may prevent breast cancer patients from developing depressive symptoms.

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